期刊简介
本杂志是由中华人民共和国卫生部主管，同济医科大学附属协和医院主办，国内外公开发行的学术性期刊，被国家科技部列为“中国科技论文统计源期刊”，被中国科学文献计量评价研究中心认定为《中国科学引文数据库》来源期刊。设有专家笔谈、临床研究、实验研究、研究报告、综述、进修苑、学术争鸣、经验介绍及病例报告等栏目。
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首页>临床血液学杂志
- 杂志名称：临床血液学杂志
- 主管单位：中华人民共和国教育部
- 主办单位：华中科技大学同济医学院附属协和医院 北京大学医学院血研所
- 国际刊号：1004-2806
- 国内刊号：42-1284/R
- 出版周期：双月刊
期刊荣誉：中国核心期刊数据库收录期刊期刊收录：国家图书馆馆藏, 万方收录(中), 上海图书馆馆藏, CA 化学文摘(美), 统计源核心期刊(中国科技论文核心期刊), 知网收录(中), 维普收录(中)
骨髓增生异常综合征的研究进展
高锦程；洪珞珈
关键词：骨髓增生异常综合征, 发病机制, 诊断分型, 风险评估
摘要：Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal disorders of bone marrow characterized by peripheral blood cytopenia and can progress to leukeamia.The clinical course of patients with MDS is characterized by wide variability reflecting the underlying genetic and biological heterogeneity of the disease.Diagnosis is currently based on the presence of peripheral blood cytopenias,peripheral blood and bone marrow dysplasia/blasts,and clonal cytogenetic abnormalities.Incomplete understanding of disease pathogenesis,the inherent biological complexity of MDS and the presence of poor performance status in the typical older patients with MDS,have been major impediments to development of effective novel therapies.In this review,we will discuss recent advances in our collective understanding of the pathogenesis,diagnosis classification and risk assessment of MDS.
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